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21c Museum Hotel St Louis is one of 2 Edit by Chase hotels in St. Louis. Its typical nightly Chase Travel rate is $197, fees included.
Independent site. Not affiliated with or endorsed by JPMorgan Chase & Co. or the hotel.
21c Museum Hotel St Louis runs lowest in January, December and February, with January the cheapest at a $177 median a night, and highest in September at $264. These are medians of the Chase Travel rates for two-night stays starting on each day of the coming year, from 293 dates on our last check.
Yes. 21c Museum Hotel St Louis is on The Edit by Chase Travel list as of our September 24, 2026 check. A prepaid Chase Travel booking here gets the Edit benefits: daily breakfast for two, a $100 property credit, an upgrade when available, and early check-in and late checkout when available.
Its typical nightly Chase Travel rate is $197, fees included: the median of the rates for two-night stays across the coming year. By month, the median runs from $177 in January to $264 in September. These are planning figures, not live quotes; check the rate on Chase Travel for your dates.
No. It is not in the 2026 select-hotel credit program, so a stay here can use the $250 Edit credit but not the second $250. The double credit hotels page lists the ones that are.
January has the lowest median Chase Travel rate here, $177 a night, followed by December and February. September is the priciest at $264. The single lowest nightly rate on our last check was $177, for a two-night stay from October 15, 2026.
Rates are medians of Chase Travel prices, fees included, for two-night stays starting on each day of the coming year; planning figures, not live quotes. How we build this data. “Compare prices” is an affiliate link: if you book through it we may earn a commission, at no cost to you. We earn nothing on Chase Travel bookings and take no card-application commissions.